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p,p’-Hexachlorobitolyl, p,p’-hexachlorobitolylketone and p,p’-hexachlorobitolylthiourea were synthesized by the radical chlorination method of Hass and McBeer. Among these compounds, wormicidal activity of p,p’-hexachlorobitolylthiourea was much more potent against Clonorchis sinensis than Hotel in vitro. In the process of the p,p’-bitolyl chlorination, alpha, alpha, alpha’-trichlorobitolyl. When gas chromatographic data from chlorinated bitolyl compounds were analyzed, linear relationship was observed between retention indices and number of chlorine in two series of odd and even numbered chlorine compounds.
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